NeoCutis Bio⋅Cream Bio-Restorative Skin Cream is ideally formulated for maturing, sensitive, stressed and irritated skin and features a naturally balanced blend of essential rejuvenating nutrients. Growth factors, antioxidants and matrix proteins, including collagen, revive skin while boosting firmness, elasticity and brightness. Skin appears more youthful as fine lines and wrinkles are visibly reduced.